Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web-based pipeline for real-time bioinformatics analysis on a computational server or lapto...

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Bibliographic Details
Main Authors: Greninger, Alexander L., Naccache, Samia N., Federman, Scot, Yu, Guixia, Mbala, Placide, Bres, Vanessa, Stryke, Doug, Bouquet, Jerome, Somasekar, Sneha, Linnen, Jeffrey M., Dodd, Roger, Mulembakani, Prime, Schneider, Bradley S., Muyembe-Tamfum, Jean-Jacques, Stramer, Susan L., Chiu, Charles Y.
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587849/