BOLD Response Selective to Flow-Motion in Very Young Infants

In adults, motion perception is mediated by an extensive network of occipital, parietal, temporal, and insular cortical areas. Little is known about the neural substrate of visual motion in infants, although behavioural studies suggest that motion perception is rudimentary at birth and matures stead...

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Main Authors:	Biagi, Laura, Crespi, Sofia Allegra, Tosetti, Michela, Morrone, Maria Concetta
Format:	Online
Language:	English
Published:	Public Library of Science 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587790/

id	pubmed-4587790
recordtype	oai_dc
spelling	pubmed-45877902015-10-02 BOLD Response Selective to Flow-Motion in Very Young Infants Biagi, Laura Crespi, Sofia Allegra Tosetti, Michela Morrone, Maria Concetta Research Article In adults, motion perception is mediated by an extensive network of occipital, parietal, temporal, and insular cortical areas. Little is known about the neural substrate of visual motion in infants, although behavioural studies suggest that motion perception is rudimentary at birth and matures steadily over the first few years. Here, by measuring Blood Oxygenated Level Dependent (BOLD) responses to flow versus random-motion stimuli, we demonstrate that the major cortical areas serving motion processing in adults are operative by 7 wk of age. Resting-state correlations demonstrate adult-like functional connectivity between the motion-selective associative areas, but not between primary cortex and temporo-occipital and posterior-insular cortices. Taken together, the results suggest that the development of motion perception may be limited by slow maturation of the subcortical input and of the cortico-cortical connections. In addition they support the existence of independent input to primary (V1) and temporo-occipital (V5/MT+) cortices very early in life. Public Library of Science 2015-09-29 /pmc/articles/PMC4587790/ /pubmed/26418729 http://dx.doi.org/10.1371/journal.pbio.1002260 Text en © 2015 Biagi et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Biagi, Laura Crespi, Sofia Allegra Tosetti, Michela Morrone, Maria Concetta
spellingShingle	Biagi, Laura Crespi, Sofia Allegra Tosetti, Michela Morrone, Maria Concetta BOLD Response Selective to Flow-Motion in Very Young Infants
author_facet	Biagi, Laura Crespi, Sofia Allegra Tosetti, Michela Morrone, Maria Concetta
author_sort	Biagi, Laura
title	BOLD Response Selective to Flow-Motion in Very Young Infants
title_short	BOLD Response Selective to Flow-Motion in Very Young Infants
title_full	BOLD Response Selective to Flow-Motion in Very Young Infants
title_fullStr	BOLD Response Selective to Flow-Motion in Very Young Infants
title_full_unstemmed	BOLD Response Selective to Flow-Motion in Very Young Infants
title_sort	bold response selective to flow-motion in very young infants
description	In adults, motion perception is mediated by an extensive network of occipital, parietal, temporal, and insular cortical areas. Little is known about the neural substrate of visual motion in infants, although behavioural studies suggest that motion perception is rudimentary at birth and matures steadily over the first few years. Here, by measuring Blood Oxygenated Level Dependent (BOLD) responses to flow versus random-motion stimuli, we demonstrate that the major cortical areas serving motion processing in adults are operative by 7 wk of age. Resting-state correlations demonstrate adult-like functional connectivity between the motion-selective associative areas, but not between primary cortex and temporo-occipital and posterior-insular cortices. Taken together, the results suggest that the development of motion perception may be limited by slow maturation of the subcortical input and of the cortico-cortical connections. In addition they support the existence of independent input to primary (V1) and temporo-occipital (V5/MT+) cortices very early in life.
publisher	Public Library of Science
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587790/
_version_	1613481582104936448

BOLD Response Selective to Flow-Motion in Very Young Infants

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