T-Cadherin Expression in Melanoma Cells Stimulates Stromal Cell Recruitment and Invasion by Regulating the Expression of Chemokines, Integrins and Adhesion Molecules

T-cadherin is a glycosyl-phosphatidylinositol (GPI) anchored member of the cadherin superfamily involved in the guidance of migrating cells. We have previously shown that in vivo T-cadherin overexpression leads to increased melanoma primary tumor growth due to the recruitment of mesenchymal stromal...

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Bibliographic Details
Main Authors: Rubina, Kseniya A., Surkova, Ekaterina I., Semina, Ekaterina V., Sysoeva, Veronika Y., Kalinina, Natalia I., Poliakov, Alexei A., Treshalina, Helena M., Tkachuk, Vsevolod A.
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586773/