FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk

The A allele of the FRAS1-related extracellular matrix protein 3 (FREM3) rs7676614 single nucleotide polymorphism (SNP) was linked to major depressive disorder (MDD) in an early genome-wide association study (GWAS), and to symptoms of psychomotor retardation in a follow-up investigation. In line wit...

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Bibliographic Details
Main Authors: Nikolova, Yuliya S., Iruku, Swetha P., Lin, Chien-Wei, Conley, Emily Drabant, Puralewski, Rachel, French, Beverly, Hariri, Ahmad R., Sibille, Etienne
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584966/