Class 3 semaphorins negatively regulate dermal lymphatic network formation

The development of a patterned lymphatic vascular network is essential for proper lymphatic functions during organ development and homeostasis. Here we report that class 3 semaphorins (SEMA3s), SEMA3F and SEMA3G negatively regulate lymphatic endothelial cell (LEC) growth and sprouting to control der...

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Bibliographic Details
Main Authors: Uchida, Yutaka, James, Jennifer M., Suto, Fumikazu, Mukouyama, Yoh-suke
Format: Online
Language:English
Published: The Company of Biologists 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582121/