Infections and Systemic Lupus Erythematosus: Binding or Sparring Partners?

Extensive work on experimental animal models clearly demonstrates that infectious agents can break immunological tolerance to self-antigens and induce autoimmune disorders, mainly systemic lupus erythematosus (SLE). The establishment of a causative link between infections and autoimmunity has been l...

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Bibliographic Details
Main Authors: Rigante, Donato, Esposito, Susanna
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581196/