Multicohort analysis of the maternal age effect on recombination

Multicohort analysis of the maternal age effect on recombination

Several studies have reported that the number of crossovers increases with maternal age in humans, but others have found the opposite. Resolving the true effect has implications for understanding the maternal age effect on aneuploidies. Here, we revisit this question in the largest sample to date us...

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Bibliographic Details
Main Authors: Martin, Hilary C., Christ, Ryan, Hussin, Julie G., O'Connell, Jared, Gordon, Scott, Mbarek, Hamdi, Hottenga, Jouke-Jan, McAloney, Kerrie, Willemsen, Gonnecke, Gasparini, Paolo, Pirastu, Nicola, Montgomery, Grant W., Navarro, Pau, Soranzo, Nicole, Toniolo, Daniela, Vitart, Veronique, Wilson, James F., Marchini, Jonathan, Boomsma, Dorret I., Martin, Nicholas G., Donnelly, Peter
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580993/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580993/

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