Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model
Like neurons, astrocytes produce and release GABA to influence neuronal signaling. At the perforant path to dentate gyrus granule neuron synapse, GABA from astrocyte was found to be a strong inhibitory factor, which impairs synaptic transmission, synaptic plasticity and memory in Alzheimer's di...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Society for Brain and Neural Science
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580748/ |