Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody

Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody

Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. Here we show the c...

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Bibliographic Details
Main Authors: Chandramouli, Sumana, Ciferri, Claudio, Nikitin, Pavel A., Caló, Stefano, Gerrein, Rachel, Balabanis, Kara, Monroe, James, Hebner, Christy, Lilja, Anders E., Settembre, Ethan C., Carfi, Andrea
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579600/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579600/

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