Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of the adhesion receptor Gpr116/ADGRF5 has remained elusive. We generated a new mouse model of constitutive Gpr116 inactivation, with a large genetic deletion encompassing exo...

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Bibliographic Details
Main Authors: Niaudet, Colin, Hofmann, Jennifer J., Mäe, Maarja A., Jung, Bongnam, Gaengel, Konstantin, Vanlandewijck, Michael, Ekvärn, Elisabet, Salvado, M. Dolores, Mehlem, Annika, Al Sayegh, Sahar, He, Liqun, Lebouvier, Thibaud, Castro-Freire, Marco, Katayama, Kan, Hultenby, Kjell, Moessinger, Christine, Tannenberg, Philip, Cunha, Sara, Pietras, Kristian, Laviña, Bàrbara, Hong, JongWook, Berg, Tove, Betsholtz, Christer
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579087/