An engineered bacterium auxotrophic for an unnatural amino acid: a novel biological containment system

Biological containment is a genetic technique that programs dangerous organisms to grow only in the laboratory and to die in the natural environment. Auxotrophy for a substance not found in the natural environment is an ideal biological containment. Here, we constructed an Escherichia coli strain th...

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Bibliographic Details
Main Author: Kato, Yusuke
Format: Online
Language:English
Published: PeerJ Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579030/