A Novel Bmal1 Mutant Mouse Reveals Essential Roles of the C-Terminal Domain on Circadian Rhythms

The mammalian circadian clock is an endogenous biological timer comprised of transcriptional/translational feedback loops of clock genes. Bmal1 encodes an indispensable transcription factor for the generation of circadian rhythms. Here, we report a new circadian mutant mouse from gene-trapped embryo...

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Bibliographic Details
Main Authors: Park, Noheon, Kim, Hee-Dae, Cheon, Solmi, Row, Hansang, Lee, Jiyeon, Han, Dong-Hee, Cho, Sehyung, Kim, Kyungjin
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578957/