Insulin activates EGFR by stimulating its interaction with IGF-1R in low-EGFR-expressing TNBC cells

Insulin activates EGFR by stimulating its interaction with IGF-1R in low-EGFR-expressing TNBC cells

The expression of epidermal growth factor receptor (EGFR) is an important diagnostic marker for triple-negative breast cancer (TNBC) cells, which lack three hormonal receptors: estrogen and progesterone receptors as well as epidermal growth factor receptor 2. EGFR transactivation can cause drug resi...

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Bibliographic Details
Main Authors: Shin, Miyoung, Yang, Eun Gyeong, Song, Hyun Kyu, Jeon, Hyesung
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578621/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578621/

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