Effect of parasitic infection on dopamine biosynthesis in dopaminergic cells

•Toxoplasma infection of neurosecretory cells increases the production of dopamine.•Infection did not change host TH or DDC.•Host DDC was observed in the parasitic vacuole in infected brain cells.•Import of host DDC may facilitate DA synthesis in the parasitic vacuole.•This would prevent toxicity du...

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Bibliographic Details
Main Authors: Martin, H.L., Alsaady, I., Howell, G., Prandovszky, E., Peers, C., Robinson, P., McConkey, G.A.
Format: Online
Language:English
Published: Elsevier Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577654/