RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure genome replication within the infected cells. RdRP function is critical not only for the virus life cycle but also for its adaptive potential. The combination of low fidelity of replication and the absence of proofr...

Full description

Bibliographic Details
Main Authors: Ferrer-Orta, Cristina, Ferrero, Diego, Verdaguer, NĂºria
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576190/