Impact of MET targeting on tumor-associated angiogenesis and growth of MET mutations-driven models of liver cancer

Deregulated expression of the MET receptor tyrosine kinase has been reported in up to 50% of patients with hepatocellular carcinoma, the most abundant form of liver cancers, and is associated with decreased survival. Consequently, MET is considered as a molecular target in this malignancy, whose pro...

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Bibliographic Details
Main Authors: Piguet, Anne-Christine, Medová, Michaela, Keogh, Adrian, Glück, Astrid A., Aebersold, Daniel M., Dufour, Jean-François, Zimmer, Yitzhak
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575919/