Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells

Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells

The MYB transcription factor plays critical roles in normal and malignant haematopoiesis. We previously showed that MYB was a direct activator of FLT3 expression within the context of acute myeloid leukaemia. During normal haematopoiesis, increasing levels of FLT3 expression determine a strict hiera...

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Bibliographic Details
Main Authors: Volpe, Giacomo, Clarke, Mary, Garcìa, Paloma, Walton, David Scott, Vegiopoulos, Alexandros, Del Pozzo, Walter, O’Neill, Laura Patricia, Frampton, Jonathan, Dumon, Stéphanie
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575200/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575200/

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