Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion

Real-time shear-wave elastography (SWE) is a newly developed method which can obtain the stiffness of tissues and organs based on tracking of shear wave propagation through a structure. Several studies have demonstrated its potential in the differentiation between diseased and normal tissue in clini...

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Main Authors:	Sun, Zhenxing, Xie, Mingxing, Xiang, Feixiang, Song, Yue, Yu, Cheng, Zhang, Yanrong, Ramdhany, Sachin, Wang, Jing
Format:	Online
Language:	English
Published:	Public Library of Science 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575189/

id	pubmed-4575189
recordtype	oai_dc
spelling	pubmed-45751892015-09-25 Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion Sun, Zhenxing Xie, Mingxing Xiang, Feixiang Song, Yue Yu, Cheng Zhang, Yanrong Ramdhany, Sachin Wang, Jing Research Article Real-time shear-wave elastography (SWE) is a newly developed method which can obtain the stiffness of tissues and organs based on tracking of shear wave propagation through a structure. Several studies have demonstrated its potential in the differentiation between diseased and normal tissue in clinical practices, however the applicability to testicular disease has not been well elucidated. We investigated the feasibility and reproducibility of SWE in the detection of testicular torsion. This prospective study comprised 15 patients with complete testicular torsion. Results obtained from SWE along with conventional gray-scale and color Doppler sonography and post-operative pathology were compared. The results revealed that (i) the size of injured testis was increased and the twisted testis parenchyma was heterogeneous. The blood flow signals in injured testis were barely visible or absent; (ii) The Young’s modulus, including Emean, Emax, Emin and SD values in the border area of torsional testis were higher than those of normal testis (Emean, 78.07±9.01kPa vs 22.0±5.10kPa; Emax,94.07±6.53kPa vs 27.87±5.78kPa; Emin, 60.73±7.84 kPa vs 18.90±4.39kPa; SD, 7.67±0.60 kPa vs 2.30±0.36 kPa, [P<0.05]); The Emax and SD values in the central area of the torsional testis were higher than the corresponding area of the normal testis (Emax, 8.23±0.30 kPa vs 3.97±0.95kPa; SD, 1.5±0.26kPa vs 0.67±0.35kPa,[P<0.05]) and Emin values was lower than those of normal testicles(0.93±0.51kPa vs 1.6±0.36kPa; [P<0.05]); (iii) The Young's modulus measurement between two physicians showed good agreement. The pathological findings were accordance with SWE measurement. SWE is a non-invasive, convenient and high reproducible method and may serve as an important alternative tool in the diagnosis and monitoring the progression of the acute scrotums, in additional to conventional Doppler sonography. Public Library of Science 2015-09-18 /pmc/articles/PMC4575189/ /pubmed/26382244 http://dx.doi.org/10.1371/journal.pone.0138523 Text en © 2015 Sun et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Sun, Zhenxing Xie, Mingxing Xiang, Feixiang Song, Yue Yu, Cheng Zhang, Yanrong Ramdhany, Sachin Wang, Jing
spellingShingle	Sun, Zhenxing Xie, Mingxing Xiang, Feixiang Song, Yue Yu, Cheng Zhang, Yanrong Ramdhany, Sachin Wang, Jing Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion
author_facet	Sun, Zhenxing Xie, Mingxing Xiang, Feixiang Song, Yue Yu, Cheng Zhang, Yanrong Ramdhany, Sachin Wang, Jing
author_sort	Sun, Zhenxing
title	Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion
title_short	Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion
title_full	Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion
title_fullStr	Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion
title_full_unstemmed	Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion
title_sort	utility of real-time shear wave elastography in the assessment of testicular torsion
description	Real-time shear-wave elastography (SWE) is a newly developed method which can obtain the stiffness of tissues and organs based on tracking of shear wave propagation through a structure. Several studies have demonstrated its potential in the differentiation between diseased and normal tissue in clinical practices, however the applicability to testicular disease has not been well elucidated. We investigated the feasibility and reproducibility of SWE in the detection of testicular torsion. This prospective study comprised 15 patients with complete testicular torsion. Results obtained from SWE along with conventional gray-scale and color Doppler sonography and post-operative pathology were compared. The results revealed that (i) the size of injured testis was increased and the twisted testis parenchyma was heterogeneous. The blood flow signals in injured testis were barely visible or absent; (ii) The Young’s modulus, including Emean, Emax, Emin and SD values in the border area of torsional testis were higher than those of normal testis (Emean, 78.07±9.01kPa vs 22.0±5.10kPa; Emax,94.07±6.53kPa vs 27.87±5.78kPa; Emin, 60.73±7.84 kPa vs 18.90±4.39kPa; SD, 7.67±0.60 kPa vs 2.30±0.36 kPa, [P<0.05]); The Emax and SD values in the central area of the torsional testis were higher than the corresponding area of the normal testis (Emax, 8.23±0.30 kPa vs 3.97±0.95kPa; SD, 1.5±0.26kPa vs 0.67±0.35kPa,[P<0.05]) and Emin values was lower than those of normal testicles(0.93±0.51kPa vs 1.6±0.36kPa; [P<0.05]); (iii) The Young's modulus measurement between two physicians showed good agreement. The pathological findings were accordance with SWE measurement. SWE is a non-invasive, convenient and high reproducible method and may serve as an important alternative tool in the diagnosis and monitoring the progression of the acute scrotums, in additional to conventional Doppler sonography.
publisher	Public Library of Science
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575189/
_version_	1613477331566854144

Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion

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