Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion

The present studies were designed to examine the effects of ClC-2 ablation on cellular morphology, parietal cell abundance, H/K ATPase expression, parietal cell ultrastructure and acid secretion using WT and ClC-2-/- mouse stomachs. Cellular histology, morphology and proteins were examined using ima...

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Bibliographic Details
Main Authors: Nighot, Meghali P., Nighot, Prashant K., Ma, Thomas Y., Malinowska, Danuta H., Shull, Gary E., Cuppoletti, John, Blikslager, Anthony T.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574764/