Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran

Recently two novel enzymes were identified in the outer mitochondrial membrane, mARC1 and mARC2. These molybdenum containing enzymes can reduce a variety of N-hydroxylated compounds, such as N-hydroxy-guanidines and sulfohydroxamic acids, as well as convert nitrite into nitric oxide (NO). However, t...

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Bibliographic Details
Main Authors: Neve, Etienne P. A., Köfeler, Harald, Hendriks, Delilah F. G., Nordling, Åsa, Gogvadze, Vladimir, Mkrtchian, Souren, Näslund, Erik, Ingelman-Sundberg, Magnus
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574727/