Clinical and In Vitro Studies on Impact of High-Dose Etoposide Pharmacokinetics Prior Allogeneic Hematopoietic Stem Cell Transplantation for Childhood Acute Lymphoblastic Leukemia on the Risk of Post-Transplant Leukemia Relapse

Clinical and In Vitro Studies on Impact of High-Dose Etoposide Pharmacokinetics Prior Allogeneic Hematopoietic Stem Cell Transplantation for Childhood Acute Lymphoblastic Leukemia on the Risk of Post-Transplant Leukemia Relapse

The impact of etoposide (VP-16) plasma concentrations on the day of allogeneic hematopoietic stem cell transplantation (allo-HSCT) on leukemia-free survival in children with acute lymphoblastic leukemia (ALL) was studied. In addition, the in vitro effects of VP-16 on the lymphocytes proliferation, c...

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Bibliographic Details
Main Authors: Sobiak, Joanna, Kazimierczak, Urszula, Kowalczyk, Dariusz W., Chrzanowska, Maria, Styczyński, Jan, Wysocki, Mariusz, Szpecht, Dawid, Wachowiak, Jacek
Format: Online
Language:English
Published: Springer Basel 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572077/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572077/

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