New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation

The origin of novel protein-coding genes de novo was once considered so improbable as to be impossible. In less than a decade, and especially in the last five years, this view has been overturned by extensive evidence from diverse eukaryotic lineages. There is now evidence that this mechanism has co...

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Bibliographic Details
Main Authors: McLysaght, Aoife, Guerzoni, Daniele
Format: Online
Language:English
Published: The Royal Society 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571571/