Dephosphorylation of Iqg1 by Cdc14 regulates cytokinesis in budding yeast

To study how actomyosin ring assembly is regulated during the cell cycle, four perfect CDK sites were mutated in IQG1. Cells expressing the mutant IQG1 allele exhibited defects in myosin contraction and cytokinesis. The data show that Iqg1 is a substrate of the phosphatase Cdc14 and that changes in...

Full description

Bibliographic Details
Main Authors: Miller, Daniel P., Hall, Hana, Chaparian, Ryan, Mara, Madison, Mueller, Alison, Hall, Mark C., Shannon, Katie B.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571329/