Proliferation-dependent positioning of individual centromeres in the interphase nucleus of human lymphoblastoid cell lines

Centromeres are not randomly distributed in interphase nuclei. High-throughput imaging provides an accurate characterization of how their organization varies as a function of the proliferation state in human lymphoblastoid cells. The results suggest the existence of mechanisms that drive the nuclear...

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Bibliographic Details
Main Authors: Ollion, Jean, Loll, François, Cochennec, Julien, Boudier, Thomas, Escudé, Christophe
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571307/