MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells
MgcRacGAP's role in regulating the spatiotemporal dynamics of active RhoA and Rac1 in epithelial cells is investigated. MgcRacGAP's GAP activity down-regulates RhoA at the furrow and both RhoA and Rac1 at cell–cell junctions in dividing epithelial cells and is required for successful cytok...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571299/ |