The rod domain is not essential for the function of plectin in maintaining tissue integrity

Plectin is a cytoskeletal linker protein that consists of a central rod domain connecting two globular domains. Rodless plectin is able to functionally compensate for the loss of full-length plectin in mice and, like full-length plectin, is able to form dimers.

Bibliographic Details
Main Authors: Ketema, Mirjam, Secades, Pablo, Kreft, Maaike, Nahidiazar, Leila, Janssen, Hans, Jalink, Kees, de Pereda, Jose M., Sonnenberg, Arnoud
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571296/