Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling

Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling

Extracellular transients of pH alterations likely mediate signal transduction in the nervous system. Neuronal acid-sensing ion channels (ASICs) act as sensors for extracellular protons, but the mechanism underlying ASIC activation remains largely unknown. Here, we show that, following activation of...

Full description

Bibliographic Details
Main Authors: Zeng, Wei-Zheng, Liu, Di-Shi, Liu, Lu, She, Liang, Wu, Long-Jun, Xu, Tian-Le
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569896/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569896/

Similar Items