[11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET)

In quantitative PET measurements, the analysis of radiometabolites in plasma is essential for determining the exact arterial input function. Diphenyl sulfide compounds are promising PET and SPECT radioligands for in vivo quantification of the serotonin transporter (SERT) and it is therefore importan...

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Bibliographic Details
Main Authors: Gourand, Fabienne, Amini, Nahid, Jia, Zhisheng, Stone-Elander, Sharon, Guilloteau, Denis, Barré, Louisa, Halldin, Christer
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569384/