Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones

How Src tyrosine kinase and cortactin control actin organization and dynamics in neuronal growth cones is not well understood. Using multiple high-resolution imaging techniques, this study shows that Src and cortactin control the persistence of lamellipodial protrusion as well as the formation, stab...

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Bibliographic Details
Main Authors: He, Yingpei, Ren, Yuan, Wu, Bingbing, Decourt, Boris, Lee, Aih Cheun, Taylor, Aaron, Suter, Daniel M.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569314/