N-glycosylation controls the function of junctional adhesion molecule-A

N-glycosylation is identified as a novel regulator of JAM-A function. Human JAM-A carries a single N-glycan at N185, which regulates the protein’s role in barrier function, migration, and leukocyte binding.

Bibliographic Details
Main Authors: Scott, David W., Tolbert, Caitlin E., Graham, David M., Wittchen, Erika, Bear, James E., Burridge, Keith
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569312/