The effects of age and dietary restriction on the tissue-specific metabolome of Drosophila

Dietary restriction (DR) is a robust intervention that extends lifespan and slows the onset of age-related diseases in diverse organisms. While significant progress has been made in attempts to uncover the genetic mechanisms of DR, there are few studies on the effects of DR on the metabolome. In rec...

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Bibliographic Details
Main Authors: Laye, Matthew J, Tran, ViLinh, Jones, Dean P, Kapahi, Pankaj, Promislow, Daniel E L
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568967/