Identification of natural inhibitors of Entamoeba histolytica cysteine synthase from microbial secondary metabolites

Amebiasis is a common worldwide diarrheal disease, caused by the protozoan parasite, Entamoeba histolytica. Metronidazole has been a drug of choice against amebiasis for decades despite its known side effects and low efficacy against asymptomatic cyst carriers. E. histolytica is also capable of surv...

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Bibliographic Details
Main Authors: Mori, Mihoko, Jeelani, Ghulam, Masuda, Yui, Sakai, Kazunari, Tsukui, Kumiko, Waluyo, Danang, Tarwadi, Watanabe, Yoshio, Nonaka, Kenichi, Matsumoto, Atsuko, Ōmura, Satoshi, Nozaki, Tomoyoshi, Shiomi, Kazuro
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568418/