Toxic Markers of Matrine Determined Using 1H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo

Matrine is one of the main bioactive alkaloids of Sophora flavescens Aiton, which has been widely used to treat various diseases in China. These diseases include viral hepatitis, liver fibrosis, cardiac arrhythmia, skin diseases, and tumors. However, matrine is also the main toxic compound of this h...

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Bibliographic Details
Main Authors: Li, Zhonghuang, Zheng, Liang, Shi, Jian, Zhang, Guiyu, Lu, Linlin, Zhu, Lijun, Zhang, Jiajie, Liu, Zhongqiu
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568042/