Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells

Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells

Malaria induces potent activation and expansion of the Vγ9Vδ2 subpopulation of γδT cells, which inhibit the Plasmodium falciparum blood cycle through soluble cytotoxic mediators, abrogating merozoite invasion capacity. Intraerythrocytic stages efficiently trigger Vγ9Vδ2 T-cell activation and degranu...

Full description

Bibliographic Details
Main Authors: Guenot, Marianne, Loizon, Séverine, Howard, Jennifer, Costa, Giulia, Baker, David A., Mohabeer, Shaneel Y., Troye-Blomberg, Marita, Moreau, Jean-François, Déchanet-Merville, Julie, Mercereau-Puijalon, Odile, Mamani-Matsuda, Maria, Behr, Charlotte
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567633/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567633/

Similar Items