Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo
We recently found that CD82 inhibits matrix metalloproteinase 9 and augments adhesion of CD34+/CD38− acute myelogenous leukemia (AML) cells to the bone marrow (BM) microenvironment. The present study found that the use of an anti-CD82 monoclonal antibody (CD82 mAb) mobilized CD34+ leukemia cells fro...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley & Sons, Ltd
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567027/ |