Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping

A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of genetic vectors and mutant strains are available. Howeve...

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Bibliographic Details
Main Authors: Gilleland, Cody L., Falls, Adam T., Noraky, James, Heiman, Maxwell G., Yanik, Mehmet F.
Format: Online
Language:English
Published: Genetics Society of America 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566274/