LncReg: a reference resource for lncRNA-associated regulatory networks

LncReg: a reference resource for lncRNA-associated regulatory networks

Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads...

Full description

Bibliographic Details
Main Authors: Zhou, Zhong, Shen, Yi, Khan, Muhammad Riaz, Li, Ao
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565966/
id pubmed-4565966
recordtype oai_dc
spelling pubmed-45659662015-09-15 LncReg: a reference resource for lncRNA-associated regulatory networks Zhou, Zhong Shen, Yi Khan, Muhammad Riaz Li, Ao Original Article Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads to complexity of literature about particular lncRNAs. Therefore, for the convenience of the researchers, we collected regulatory relationships of the lncRNAs and built a database called ‘LncReg’. This database is developed by collecting 1081 validated lncRNA-associated regulatory entries, including 258 non-redundant lncRNAs and 571 non-redundant genes. With regulatory relationships information, LncReg can provide overall perspectives of regulatory networks of lncRNAs and comprehensive data for bioinformatics research, which is useful for understanding the functional roles of lncRNAs. Oxford University Press 2015-09-10 /pmc/articles/PMC4565966/ /pubmed/26363021 http://dx.doi.org/10.1093/database/bav083 Text en © The Author(s) 2015. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zhou, Zhong
Shen, Yi
Khan, Muhammad Riaz
Li, Ao
spellingShingle Zhou, Zhong
Shen, Yi
Khan, Muhammad Riaz
Li, Ao
LncReg: a reference resource for lncRNA-associated regulatory networks
author_facet Zhou, Zhong
Shen, Yi
Khan, Muhammad Riaz
Li, Ao
author_sort Zhou, Zhong
title LncReg: a reference resource for lncRNA-associated regulatory networks
title_short LncReg: a reference resource for lncRNA-associated regulatory networks
title_full LncReg: a reference resource for lncRNA-associated regulatory networks
title_fullStr LncReg: a reference resource for lncRNA-associated regulatory networks
title_full_unstemmed LncReg: a reference resource for lncRNA-associated regulatory networks
title_sort lncreg: a reference resource for lncrna-associated regulatory networks
description Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads to complexity of literature about particular lncRNAs. Therefore, for the convenience of the researchers, we collected regulatory relationships of the lncRNAs and built a database called ‘LncReg’. This database is developed by collecting 1081 validated lncRNA-associated regulatory entries, including 258 non-redundant lncRNAs and 571 non-redundant genes. With regulatory relationships information, LncReg can provide overall perspectives of regulatory networks of lncRNAs and comprehensive data for bioinformatics research, which is useful for understanding the functional roles of lncRNAs.
publisher Oxford University Press
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565966/
_version_ 1613474678587785216

Similar Items