Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

Recent advances in the study of the CRISPR/Cas9 system have provided a precise and versatile approach for genome editing in various species. However, the applicability and efficiency of this method in large animal models, such as the goat, have not been extensively studied. Here, by co-injection of...

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Bibliographic Details
Main Authors: Wang, Xiaolong, Yu, Honghao, Lei, Anmin, Zhou, Jiankui, Zeng, Wenxian, Zhu, Haijing, Dong, Zhiming, Niu, Yiyuan, Shi, Bingbo, Cai, Bei, Liu, Jinwang, Huang, Shuai, Yan, Hailong, Zhao, Xiaoe, Zhou, Guangxian, He, Xiaoling, Chen, Xiaoxu, Yang, Yuxin, Jiang, Yu, Shi, Lei, Tian, Xiue, Wang, Yongjun, Ma, Baohua, Huang, Xingxu, Qu, Lei, Chen, Yulin
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564737/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564737/

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