Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches

A sizable fraction of testicular germ cell tumour (TGCT) risk is expected to be explained by heritable factors. Recent genome-wide association studies (GWAS) have successfully identified a number of common SNPs associated with TGCT. It is however, unclear how much common variation there is left to b...

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Bibliographic Details
Main Authors: Litchfield, Kevin, Thomsen, Hauke, Mitchell, Jonathan S., Sundquist, Jan, Houlston, Richard S, Hemminki, Kari, Turnbull, Clare
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563562/