Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells
•β cell leptin receptors play a minor role in glucose homeostasis.•α cell leptin receptors are not involved in responses to hypoglycaemia.•Body weight maintenance does not require leptin action on GLP-1-secreting cells.
| Main Authors: | , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563029/ |