Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis

Oxidative stress plays a critical role in ischemia/reperfusion-injury, atherosclerosis, and aging. It causes cell damage that leads to apoptosis via uncertain mechanisms. Because conditioned medium from cardiac myocytes subjected to hypoxia/reoxygenation induces extensive apoptosis of cardiac myocyt...

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Bibliographic Details
Main Authors: Seko, Yoshinori, Fujimura, Tsutomu, Yao, Takako, Taka, Hikari, Mineki, Reiko, Okumura, Ko, Murayama, Kimie
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562266/