Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors

Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors

MicroRNAs regulate eukaryotic gene expression upon pairing onto target mRNAs. This targeting is influenced by the complementarity between the microRNA “seed” sequence at its 5′ end and the seed-matching sequences in the mRNA. Here, we assess the efficiency and specificity of 8-mer locked nucleic aci...

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Bibliographic Details
Main Authors: Staedel, Cathy, Varon, Christine, Nguyen, Phu Hung, Vialet, Brune, Chambonnier, Lucie, Rousseau, Benoît, Soubeyran, Isabelle, Evrard, Serge, Couillaud, Franck, Darfeuille, Fabien
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561653/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561653/

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