TREM2 in CNS homeostasis and neurodegenerative disease

Myeloid-lineage cells accomplish a myriad of homeostatic tasks including the recognition of pathogens, regulation of the inflammatory milieu, and mediation of tissue repair and regeneration. The innate immune receptor and its adaptor protein—triggering receptor expressed on myeloid cells 2 (TREM2) a...

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Bibliographic Details
Main Authors: Painter, Meghan M., Atagi, Yuka, Liu, Chia-Chen, Rademakers, Rosa, Xu, Huaxi, Fryer, John D., Bu, Guojun
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560063/