Benfotiamine upregulates antioxidative system in activated BV-2 microglia cells

Chronic microglial activation and resulting sustained neuroinflammatory reaction are generally associated with neurodegeneration. Activated microglia acquires proinflammatory cellular profile that generates oxidative burst. Their persistent activation exacerbates inflammation, which damages healthy...

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Bibliographic Details
Main Authors: Bozic, Iva, Savic, Danijela, Stevanovic, Ivana, Pekovic, Sanja, Nedeljkovic, Nadezda, Lavrnja, Irena
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559599/