Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo
The production of high affinity, class switched antibodies produced by B cells hinges on the effective differentiation of T follicular helper (Tfh) cells. Here we define conditions specifically enhancing Tfh differentiation and providing protection in a model of influenza infection. Tfh responses we...
Main Authors: | , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558563/ |