Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo

The production of high affinity, class switched antibodies produced by B cells hinges on the effective differentiation of T follicular helper (Tfh) cells. Here we define conditions specifically enhancing Tfh differentiation and providing protection in a model of influenza infection. Tfh responses we...

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Bibliographic Details
Main Authors: Benson, Robert A, MacLeod, Megan KL, Hale, Benjamin G, Patakas, Agapitos, Garside, Paul, Brewer, James M
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558563/