Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease

Animals that accurately model human disease are invaluable in medical research, allowing a critical understanding of disease mechanisms, and the opportunity to evaluate the effect of therapeutic compounds in pre-clinical studies. Many types of animal models are used world-wide, with the most common...

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Bibliographic Details
Main Authors: Pinnapureddy, Ashish R., Stayner, Cherie, McEwan, John, Baddeley, Olivia, Forman, John, Eccles, Michael R.
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557632/