Formation of helical membrane tubes around microtubules by single-headed kinesin KIF1A

The kinesin-3 motor KIF1A is in charge of vesicular transport in neuronal axons. Its single-headed form is known to be very inefficient due to the presence of a diffusive state in the mechanochemical cycle. However, recent theoretical studies have suggested that these motors could largely enhance fo...

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Bibliographic Details
Main Authors: Oriola, David, Roth, Sophie, Dogterom, Marileen, Casademunt, Jaume
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557341/