Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer's disease pathology

Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer's disease pathology

Alzheimer's disease (AD) is a neurodegenerative disorder in which chronic neuroinflammation contributes to disease escalation. Nevertheless, while immunosuppressive drugs have repeatedly failed in treating this disease, recruitment of myeloid cells to the CNS was shown to play a reparative role...

Full description

Bibliographic Details
Main Authors: Baruch, Kuti, Rosenzweig, Neta, Kertser, Alexander, Deczkowska, Aleksandra, Sharif, Alaa Mohammad, Spinrad, Amit, Tsitsou-Kampeli, Afroditi, Sarel, Ayelet, Cahalon, Liora, Schwartz, Michal
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557123/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557123/

Similar Items