Structure-Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes
Protein–protein interactions (PPIs) are involved at all levels of cellular organization, thus making the development of PPI inhibitors extremely valuable. The identification of selective inhibitors is challenging because of the shallow and extended nature of PPI interfaces. Inhibitors can be obtaine...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
WILEY-VCH Verlag
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557054/ |