Marine Indole Alkaloids
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplasti...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
MDPI
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557006/ |
id |
pubmed-4557006 |
---|---|
recordtype |
oai_dc |
spelling |
pubmed-45570062015-09-03 Marine Indole Alkaloids Netz, Natalie Opatz, Till Review Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in addition to the action on human enzymes and receptors. The newly isolated indole alkaloids of marine origin since the last comprehensive review in 2003 are reported, and biological aspects will be discussed. MDPI 2015-08-06 /pmc/articles/PMC4557006/ /pubmed/26287214 http://dx.doi.org/10.3390/md13084814 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Netz, Natalie Opatz, Till |
spellingShingle |
Netz, Natalie Opatz, Till Marine Indole Alkaloids |
author_facet |
Netz, Natalie Opatz, Till |
author_sort |
Netz, Natalie |
title |
Marine Indole Alkaloids |
title_short |
Marine Indole Alkaloids |
title_full |
Marine Indole Alkaloids |
title_fullStr |
Marine Indole Alkaloids |
title_full_unstemmed |
Marine Indole Alkaloids |
title_sort |
marine indole alkaloids |
description |
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in addition to the action on human enzymes and receptors. The newly isolated indole alkaloids of marine origin since the last comprehensive review in 2003 are reported, and biological aspects will be discussed. |
publisher |
MDPI |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557006/ |
_version_ |
1613471761733517312 |