Marine Indole Alkaloids

Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplasti...

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Main Authors: Netz, Natalie, Opatz, Till
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557006/
id pubmed-4557006
recordtype oai_dc
spelling pubmed-45570062015-09-03 Marine Indole Alkaloids Netz, Natalie Opatz, Till Review Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in addition to the action on human enzymes and receptors. The newly isolated indole alkaloids of marine origin since the last comprehensive review in 2003 are reported, and biological aspects will be discussed. MDPI 2015-08-06 /pmc/articles/PMC4557006/ /pubmed/26287214 http://dx.doi.org/10.3390/md13084814 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Netz, Natalie
Opatz, Till
spellingShingle Netz, Natalie
Opatz, Till
Marine Indole Alkaloids
author_facet Netz, Natalie
Opatz, Till
author_sort Netz, Natalie
title Marine Indole Alkaloids
title_short Marine Indole Alkaloids
title_full Marine Indole Alkaloids
title_fullStr Marine Indole Alkaloids
title_full_unstemmed Marine Indole Alkaloids
title_sort marine indole alkaloids
description Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in addition to the action on human enzymes and receptors. The newly isolated indole alkaloids of marine origin since the last comprehensive review in 2003 are reported, and biological aspects will be discussed.
publisher MDPI
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557006/
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